Comparison between conventional and diffusion-weighted magnetic resonance imaging in predicting grade and stage of urinary bladder cancer

Abstract Background Urinary bladder cancer is the second most common neoplasm of urinary tract. Tumor staging and regional disease spread are strongest predictors treatment outcome. Our study aims to compare diagnostic performance conventional diffusion-weighted magnetic resonance imaging (DW-MRI), using a 3T MR scanner, in grading with histopathologic correlation. Results The sensitivity, specificity, accuracy combined use HR T2WI DWI were better than only differentiate T1 stage from further stages (95%, 100%, 98%, respectively). Differentiating organ confined (T1 T2 stages) tumors extravesical extension was when both (accuracy 100% 93%, Kappa agreement (0.963 0.496 Grade III lesions showed statistically significant lower ADC values grades I II cut off value ≤ 0.95 × 10 −3 mm 2 /s. No difference found between transitional cell carcinoma (TSC) other types. Conclusion Combined provides more accurate prediction aggressiveness certain histologic grade (GIII lesions) values. 3 T scanners have potential achieve higher capability evaluation cancer.